[one_full last=”yes” spacing=”yes” center_content=”no” hide_on_mobile=”no” background_color=”#ffffff” background_image=”” background_repeat=”no-repeat” background_position=”left top” border_size=”0px” border_color=”” border_style=”solid” padding=”” margin_top=”” margin_bottom=”” animation_type=”0″ animation_direction=”down” animation_speed=”0.1″ class=”” id=””][fusion_text]
List of BioPharma Industries in India
S. No. | Company/Collaborator(s) Name | Product/Process Description |
Health Care | ||
Drugs/Therapeutics | ||
1. | ARA Healthcare Limited, Gurgaon | Anti- TNF-alpha Antibody scFv for treatment of Inflammatory Diseases |
2. | TCG Life Sciences Limited, Kolkata | Process for Asymmetric Synthesis of Hexahydrobenzophenanthrenes, Dopamine D1 Agonists |
3. | Bharat Serums and Vaccines Limited, Mumbai | Technology development for implant based sustained release formulations incorporating therapeutic peptides/ recombinant proteins |
4. | (i) Amrita Therapeutics Limited, Ahmedabad
(ii) National Institute of Immunology, New Delhi (iii) B.V. Patel PERD Centre, Ahmedabad |
Identification and Development of Promiscuous Anticancer Compounds from Microorganisms |
5. | Life Care Innovations Pvt. Ltd., Gurgaon | Production of poly (lactide-co-glycolide) nanoparticles (PLG-NP )and poly (lactide-co-glycolide) nanoparticles encapsulating antitubercular drugs (rifampicin, isoniazid and pyrazinamide- PLG-NP-ATDs) in GMP facilities |
6. | Incozen Therapeutics Pvt. Ltd., Hyderabad | Discovery and Development of potent, selective and novel c-Met kinase inhibitors in cancer |
7. | (i) Sphaera, Manesar
(ii) Leadinvent, Delhi (iii) International Centre for Genetic Engineering and Biotechnology , New Delhi |
Novel combination therapy for treatment of resistant and non responsive cancers |
8. | Rasayani Biologics Pvt. Ltd., Pune | Evaluation of Platinum Nano Particles for the Treatment of Hormone Refractory Prostate Cancer |
9. | Panacea Biotec Ltd., New Delhi | Development of novel peptide based topical gel for the treatment of alopecia |
10. | Anthem Biosciences Pvt. Ltd., Bangalore | Ketoreductases – Whole Cell Biotransformation for chiral chemistry |
11. | (i) Bhat Biotech (I) Pvt. Ltd., Bangalore
(ii) Manipal Life Sciences Centre, Manipal |
Design and expression of humanied antibodies against soluble Interleukin-6^ soluble gp130 in Bacterial and Animal Cell lines |
12. | (i) Mitra Biotech Pvt. Ltd., Bangalore
(ii) Anthem Biosciences Pvt. Ltd., Bangalore |
Development of PAT-1102, a novel HDAC inhibitor for the treatment of cancer |
13. | Crystalin Research Pvt. Ltd., Hyderabad | Pre-Clinical studies of novel anticancer drug cocrystal |
Vaccines | ||
14. | Virchow Biotech Private Ltd., Hyderabad | Mucosal Vaccine For HPV |
15. | Gennova Biopharmaceuticals Limited, Pune | Recombinant Human Papillomavirus vaccine |
16. | (i) Serum Institute of India Limited, Pune
(ii) Indian Institute of Science, Bangalore (iii) National Institute of Immunology, New Delhi |
Immunogens and monoclonal antibodies against pandemic H1N1 |
17. | Tergene Biotech Pvt. Ltd., Secunderabad | Development of an Affordable, Asia specific 15 valent Pneumococcal Ploysaccharide – CRM 197 protein conjugate Vaccine |
18. | Tergene Biotech Pvt. Ltd., Secunderabad – Phase 2 | Development of an Affordable, Asia specific 15 valent Pneumococcal Polysaccharide – CRM 197 Protein Conjugate Vaccine |
19. | Panacea Biotec Ltd., New Delhi | Development of safe and highly efficacious 13-valent pneumococcal conjugate vaccine against Streptococcus pneumoniae infections |
20. | Serum Institute of India Ltd., Pune | Development of HPV Vaccine |
Diagnostics | ||
21. | Bigtec Private Limited, Bangalore | Point-of-Care detection of infectious disease using handheld microPCR |
22. | Amar Immunodiagnostics Pvt. Ltd., Hyderabad | Immunodiagnostic kits for detection of autoimmune diseases |
23. | Abexome, Bangalore | Establishment of vitro phamacological Assay platform for biosimilars |
24. | Revelations Biotech Pvt. Ltd., Hyderabad | Development of low cost rapid quantitative PCR technology for molecular diagnosis |
25. | Chromous Biotech Pvt. Ltd., Bangalore | Multiplex Fast-PCR based diagnosis and prognosis of tuberclulosis |
26. | (i) C-CAMP, Bangalore
(ii) Indian Institute of Technology, Madras |
Flow analyzer |
27. | Transasia Biomedical Ltd., Mumbai | To develop novel 3rd Generation HIV (Antibody) & 4th generation (HIV Antigen and Antibody) immunoassay forma using flash type chemiluminiscence and magnetic particles as matrix |
28. | (i) Design Innova, New Delhi
(ii) International Centre for Genetic Engineering and Biotechnology, New Delhi |
Design and development of an affordable fluorescence reader for point-of-care diagnostics |
29. | (i) Janacare Solutions Pvt. Ltd., New Delhi
(ii) All India Institute of Medical Sciences, New Delhi (iii) Narayana Hrudayalaya Hospital City, Bangalore |
DXPhone |
30. | Optra Systems Pvt. Ltd., Pune
|
ONCOSCAN – Digital Oncopathology slide Scanner
|
Clinical Trials | ||
31. | (i) Bharat Biotech International Limited, Hyderabad
(ii) Christian Medical College, Vellore (iii) KEM Hospital Research Centre, Pune (iv) Translational Health Science and Technology Institute, New Delhi |
Rotavirus Vaccine Candidate 116E |
32. | Torrent Pharmaceuticals Limited, Gandhinagar | A strategy for the Development of Alternative treatment for Heart failure complicated with diabetes mellitus |
33. | Torrent Pharmaceuticals Limited, Gandhinagar | Clinical development of TRC150094, a novel Diiodothyronine (T2) analogue, for the treatment of cardiovascular (CV) risk factors defined by Metabolic Syndrome (MS). |
34. | Biocon Limited, Bangalore | A Multicenter, Randomized, Double-Blind, Placebo Control Study of IN-105 tablets [oral insulin] in Patients with Type 2 Diabetes Mellitus who have inadequate Glycemic Control on Optimal doses of Extended Release Metformin Tablets. |
35. | Biocon Limited, Bangalore | Open label, randomized, Multicentric studies to Comapre safety and efficacy of Recombinant insulin aspart-biphasic and regular with NovoLog® Mix 70/30 and NovoRapid in T1DM and T2DM patients |
36. | Panacea Biotec Limited, New Delhi | H1N1 pandemic influenza vaccine |
37. | V-Life Sciences Technology Pvt. Ltd., Pune | Clinical Investigation of Galnobax for the treatment of Diabetic foot Ulcers |
38. |
Biological E Limited., Hyderabad |
A Multicentric, Parallel Randomised (2:1) Open Label Phase III Clinical Study To Evaluate The Immunogenicity And Safety Of BE’s Inactivated JE Vaccine In Healthy ≥1 To |
39. | Cadila Pharmaceuticals Ltd., Ahmedabad | Clinical Development of Influenza Vaccines |
Biogenerics/Biosimilars | ||
40. | Sun Pharmaceutical Industries Ltd., Gujarat | Bevaciumab upto Pre-clinical studies |
41. | Gennova Biopharmaceuticals Limited, Pune | Bio-similar interferon beta 1a: process development |
42. | Clonz Biotech Pvt. Ltd., Hyderabad | Production of ranibizumab a recombinant humanized Anti-VEGF monoclonal antibody fragment (recombinant huFab V2) expressed in Hansenula Ploymorpha` |
43. | Navya Biologicals Pvt. Ltd. | Development of novel intensified technology platform for production of low cost Mabs |
44. | Wockhardt Limited, Aurangabad | Development of animal component free biosimilar recombinant protein therapeutics using mammalian platform technology |
45. | Serum Institute of India Limited, Pune | Clinical Development of Polysialylated Erythropoietin |
46. | IMGENEX India Pvt. LTd., Bhubaneswar | Development of High Expression plasmid vectors for production of biosimilar herceptin and other recombinant proteins and antibodies |
47. | Revelations Biotech Pvt. Ltd., Hyderabad | Development of Novel and Economic process for production of recombinant human Insulin |
48. | Intas Biopharmaceuticals Pvt. Ltd., Ahemedabad | Mucosal formulations of Parathyroid hormone (PTH) |
49. | Vivo Biotech Ltd., Andhra Pradesh | Optimization of Scale-up/Purification and clinical grade material generation of recombinant Urate Oxidase |
50. | Inbiopro Solutions Pvt. Ltd., Bangalore | Interferon Beta 1b process development |
Stemcells | ||
51. | Stempeutics Research Pvt. Ltd., Bangalore | A Randomized, Double Blind, multicentric, placebo controlled, Phase-II study assessing the safety and efficacy of Intraarterial (Hepatic) Ex-vivo cultured adult allogenic mesenchymal stem cells in patients with liver cirrhosis
|
52. | Ravindranath GE Medical Associates Pvt. Ltd., Hyderabad | Functional evaluation of autologous cell based therapy in cardiovascular diseases – Molecular imaging (An innovative non-invasiv technology” |
Others | ||
53. | Perfint Healthcare Pvt. Ltd., Chennai | Solution for planning, execution and confirmation of targeted ablation therapy |
54. | Strand Life Science, Bangalore | Hepatotoxicity prediction platform |
55. | Frontier Lifeline Private Limited, Chennai | Porcine Pulmonary Xenograft as a Conduit in Cardiovascular Surgery |
56. | (i) Vinvish Technologies Pvt. Ltd., Trivendrum
(ii) Centre for Earth Sciences, Trivandrum (iii) Regional Cancer Centre, Thiruvananthapuram |
Design and Development of photo dynamic therapy laser system |
57. | Agada Medical Technologies, Chennai | Percutaneous Aortic Valve Technology |
58. | Merkel Haptic Systems Pvt. Ltd., Chennai | Hi-fidelity affordable mannequin for effective CPR (Cardiopulmonary Resuscitation) Training |
Agriculture | ||
Transgenics | ||
1. | Maharashtra Hybrid Seeds Company Limited, Jalna | Stress tolerant rice |
2. | Maharashtra Hybrid Seeds Company Limited | Development of Sucking Insect Pest tolerant rice and cotton |
3. | Metahelix Life Sciences Private Limited, Bangalore | A proposal for funding of deregulation trials of transgenic rice events expressing Metahelix synthetic Cry1C, Cry1Ac and Cry1Ab genes for tolerance to rice yellow stem borer, Scirpophaga incertulas |
4. | Metahelix Life Sciences Private Limited, Bangalore | Deregul action trials phase I of transgenic maize events expressing Metahelix Synthetic Cry1C, Cry1Ac and Cry1Ab Genes for tolerance to stem and cob borers |
5. | (i) Bioseed Research India Ltd., Hyderabad
(ii) International Centre for Genetic Engineering and Biotechnology , New Delhi |
Development of rice hybrids with improved drought and salinity stress tolerance
|
6. | JK Agri Genetics Ltd., Hyderabad | Development of Bt-rice with two cry genes |
7. | (i) Mother Dairy Fruit and Vegetable Private Limited, Noida
(ii) University of Delhi, South Campus, New Delhi |
To conduct confined field trials and biosafety studies on genetically engineered Brassica juncea (Male sterility and restorer lines as pollination control mechanism) for heterosis breeding and yield improvement |
Marker Assisted Selection | ||
8. | *Advanta India Limited, Secunderabad | Multistacking genes to develop engineered rice with enhanced drought and multiple disease and pest resistance |
9. | Kaveri Seeds Company Ltd., Secunderabad | Development of biotic stress resistant rice through conjunct use of bio-and hybrid technologies |
10. | (i) Nirmal Seeds Pvt. Ltd., Jalgaon
(ii) The Energy and Resources Institute, New Delhi |
Development of nutritionally improved mustard (Brassica juncea) varieties/hybrids having low erucic acid and low glucosinolate content using marker assisted selection |
11. | Kaveri Seeds Company Ltd., Secunderabad | Marker-assisted dissection of genetic basis of yield and improving yield potential under drought stress in Maize
|
12. | (i) Krishidhan Seeds pvt. Ltd., Jalna
(ii) ICRISAT, Andhra Pradesh
|
Genomics assisted accelerated product development of high yeilding pigeonpea hybrids
|
RNAi | ||
13. | (i) **Advanta India Limited, Secunderabad
(ii) Indian Agriculture Research Institute, New Delhi |
RNAi and other cuting edge technological interventions to develop insect-pest diseases & viruses tolerant tomato hybrids for Indian & International markets |
14. | (i) Sri Biotech Laboratories India Ltd., Hyderabad
(ii) University of Delhi South Campus, Delhi |
Control of Shoot and Fruit Borer Insect Pest (Leucinodes orbonalis Guenée) in Brinjal Through RNA interference |
15. | (i) Ankur Seeds Pvt. Ltd., Nagpur
(ii) International Centre for Genetic Engineering and Biotechnology , New Delhi |
Third generation RNAi for engineering Tomato leaf curl (ToLCV) and tospovirus (GBNV) resistance in tomato |
16. | (i) Nirmal Seeds Pvt. Ltd., Jalgaon
(ii) University of Delhi, South Campus, New Delhi |
Development of viral resistant okra using RNAi approached |
Others | ||
17. | (i) Bejo Sheetal Seeds Private Limited, Jalna
(ii) International Centre for Genetic Engineering and Biotechnology , New Delhi |
Development of ‘Herbicide & Stress tolerant’ transgenic Onion |
18. | (i) Sri Biotech Laboratories India Ltd., Hyderabad
(ii) International Crops Research Institute for the Semi-Arid Tropics, Hyderabad |
Development of Actinomycetes based metabolites as delivery systems for soil health management in Groundnut |
19. | Chromous Biotech Pvt. Ltd., Bangalore | Multiplexed fast-PCR based detection kit for major plant virus groups in India. |
20. | AP organics Pvt. Ltd., Punjab | Project on value addition including potential neutraceuticals from derivatives of rice |
21. | (i) Saveer Biotech, Greater Noida
(ii) Indian Statistical Institute, Kolkata |
Commercial Scale Production of Nanopesticides and Nanofungicides for Indian Agro-industry |
22. | Tata Chemicals Limited, Pune | Inorganic and polymer nano-composites for micronutrient & pesticide delivery: Boosting crop health and yield. |
23. | Stellence PharmScience Ltd., Bangalore | Development of a bio-efficacious value-added novel neem-based biopesticide formulation |
Industrial | ||
1. | Rossari Biotech Ltd., Mumbai | Viable Enzymes production using Agro waste/produce as raw material of Industrial/Feed and health care use with large viable Market/demand |
2. | Abhay Cotex India Pvt., Maharashtra | Single step extraction of cottonseed with miscella refining |
3. | (i) Anil Ltd., Ahmedabad
(ii) National Chemical Laboratory (NCL), Pune |
Development of Value added Corn steep liquor and powder suitable for food and fermentation industry upto pilot scale (1 TPD) |
4. | Myko Tech Pvt. Ltd., Mapusa
|
Enhanced production of extra-cellular melanin from various fungal sources for protection against UV and gamma radiations
|
Energy | ||
1. | Avesthagen Limited, Bangalore | Development of Self-glucogenic Pearl Millet adapted for marginal lands |
2. | Richcore Lifesciences Pvt Ltd., Bangalore | A process for Enhanced Ethanol Yield from Molasses Fermentation |
3. | Nagarjuna Fertilizers and Chemical Limited, Hyderabad | Biological Hydrogen Production |
4. | (i) Bharat Petroleum Corporation Limited, Greater Noida
(ii) The Energy and Resources institute, New Delhi |
Butanol production from lignocellulosic biomass |
5. | Thermax Limited, Pune | Anaerobic Membrane Bioreactor (AnMBR) for Waste to Energy Solutions |
6. | India Glycols Limited, Kashipur | Setting up a 10 ton Lignocellulosic biomass/day processing plant to produce about 3000 Litre ethanol/day |
7. | SPC Biotech, Hyderabad | Bioconversion of Agricultural Waste from Mango kernel, to Polylactic acid a bio-plastic |
8. | Sea6 Energy, chennai | Cost-effective offshore biomass production and bio-conversion to fuel – Bioenergy |
9. | Praj matrix, Pune | Lignocellulosic Biomass to Ethanol Technology: Simultaneous Saccharification and Fermentation |
Capacity Building through Infrastructure Support | ||
1. | Span Diagnostics Limited, Surat | Establishment of cGMP compliant Bioprocess Facility for large-scale production of Microbial antigens and Monoclonal antibodies |
2. | Intas Biopharmaceuticals Private Limited, Ahmedabad | Facility for high end structural and functional characterization of protein therapeutics and peptides |
3. | Gennova Biopharmaceuticals Limited, Pune | State of art cGMP prodution facility metting regulatory requirement for production of recombinant bio-therapeutics |
4. | Celestial Biologicals Ltd., Ahmedabad | Scale-up of Plasma Fractionatin Facility for High Value Product |
Bio-informatics | ||
1. | (i) Persistent Systems, Maharashtra
(ii) Indian Institute of Technology (IIT), Mumbai (iii) Indian Institute of Science Education and Research (IISER), Pune (iv) National Bureau of Animal Genetic Resources (NBAGR), Haryana |
SanGeniX: A comprehensive next generation sequence (NGS) data analysis solution |
[/fusion_text][/one_full]