List of BioPharma Industries in India

S. No. Company/Collaborator(s) Name Product/Process Description
Health Care
Drugs/Therapeutics
1. ARA Healthcare Limited, Gurgaon Anti- TNF-alpha Antibody scFv for treatment of Inflammatory Diseases
2. TCG Life Sciences Limited, Kolkata Process for Asymmetric Synthesis of Hexahydrobenzophenanthrenes, Dopamine D1 Agonists
3. Bharat Serums and Vaccines Limited, Mumbai Technology development for implant based sustained release formulations incorporating therapeutic peptides/ recombinant proteins
4. (i)        Amrita Therapeutics Limited, Ahmedabad

(ii)      National Institute of Immunology, New Delhi

(iii)    B.V. Patel PERD Centre, Ahmedabad

Identification and Development of Promiscuous Anticancer Compounds from Microorganisms
5. Life Care Innovations Pvt. Ltd., Gurgaon Production of poly (lactide-co-glycolide) nanoparticles       (PLG-NP )and poly (lactide-co-glycolide) nanoparticles encapsulating antitubercular drugs (rifampicin, isoniazid and pyrazinamide- PLG-NP-ATDs) in GMP facilities
6. Incozen Therapeutics Pvt. Ltd., Hyderabad Discovery and Development of potent, selective and novel c-Met kinase inhibitors in cancer
7. (i)     Sphaera, Manesar

(ii)   Leadinvent, Delhi

(iii) International Centre for Genetic Engineering and Biotechnology , New Delhi

 

Novel combination therapy for treatment of resistant and non responsive cancers

8. Rasayani Biologics Pvt. Ltd., Pune Evaluation of Platinum Nano Particles for the Treatment of Hormone Refractory Prostate Cancer
9. Panacea Biotec Ltd., New Delhi Development of novel peptide based topical gel for the treatment of alopecia
10. Anthem Biosciences Pvt. Ltd., Bangalore Ketoreductases – Whole Cell Biotransformation for chiral chemistry
11. (i)     Bhat Biotech (I) Pvt. Ltd., Bangalore

(ii)   Manipal Life Sciences Centre, Manipal

Design and expression of humanied antibodies against soluble Interleukin-6^ soluble gp130 in Bacterial and Animal Cell lines
12. (i)     Mitra Biotech Pvt. Ltd., Bangalore

(ii)   Anthem Biosciences Pvt. Ltd., Bangalore

Development of PAT-1102, a novel HDAC inhibitor for the treatment of cancer
13. Crystalin Research Pvt. Ltd., Hyderabad Pre-Clinical studies of novel anticancer drug cocrystal
Vaccines
14. Virchow Biotech Private Ltd., Hyderabad Mucosal Vaccine For HPV
15. Gennova Biopharmaceuticals Limited, Pune Recombinant Human Papillomavirus vaccine
16. (i)        Serum Institute of India Limited, Pune

(ii)      Indian Institute of Science, Bangalore

(iii)    National Institute of Immunology, New Delhi

Immunogens and monoclonal antibodies against pandemic H1N1
17. Tergene Biotech Pvt. Ltd., Secunderabad Development of an Affordable, Asia specific 15 valent Pneumococcal Ploysaccharide – CRM 197 protein conjugate Vaccine
18. Tergene Biotech Pvt. Ltd., Secunderabad – Phase 2 Development of an Affordable, Asia specific 15 valent Pneumococcal Polysaccharide – CRM 197 Protein Conjugate Vaccine
19. Panacea Biotec Ltd., New Delhi Development of safe and highly efficacious 13-valent pneumococcal conjugate vaccine against Streptococcus pneumoniae infections
20. Serum Institute of India Ltd., Pune Development of HPV Vaccine
Diagnostics
21. Bigtec Private Limited, Bangalore Point-of-Care detection of infectious disease using handheld microPCR
22. Amar Immunodiagnostics Pvt. Ltd., Hyderabad Immunodiagnostic kits for detection of autoimmune diseases
23. Abexome, Bangalore Establishment of vitro phamacological Assay platform for biosimilars
24. Revelations Biotech Pvt. Ltd., Hyderabad Development of low cost rapid quantitative PCR technology for molecular diagnosis
25. Chromous Biotech Pvt. Ltd., Bangalore Multiplex Fast-PCR based diagnosis and prognosis of tuberclulosis
26. (i)     C-CAMP, Bangalore

(ii)   Indian Institute of Technology, Madras

 

Flow analyzer

27. Transasia Biomedical Ltd., Mumbai To develop novel 3rd Generation HIV (Antibody) & 4th generation (HIV Antigen and Antibody) immunoassay forma using flash type chemiluminiscence and magnetic particles as matrix
28. (i)     Design Innova, New Delhi

(ii)   International Centre for Genetic Engineering and Biotechnology, New Delhi

Design and development of an affordable fluorescence reader for point-of-care diagnostics
29. (i)     Janacare Solutions Pvt. Ltd., New Delhi

(ii)   All India Institute of Medical Sciences, New Delhi

(iii) Narayana Hrudayalaya Hospital City, Bangalore

 

 

DXPhone

30. Optra Systems Pvt. Ltd., Pune

 

ONCOSCAN – Digital Oncopathology slide Scanner

 

Clinical Trials
31. (i)     Bharat Biotech International Limited, Hyderabad

(ii)   Christian Medical College, Vellore

(iii) KEM Hospital Research Centre, Pune

(iv) Translational Health Science and Technology Institute, New Delhi

Rotavirus Vaccine Candidate 116E
32. Torrent Pharmaceuticals Limited, Gandhinagar A strategy for the Development of Alternative treatment for Heart failure complicated with diabetes mellitus
33. Torrent Pharmaceuticals Limited, Gandhinagar Clinical development of TRC150094, a novel Diiodothyronine (T2) analogue, for the treatment of cardiovascular (CV) risk factors defined by Metabolic Syndrome (MS).
34. Biocon Limited, Bangalore A Multicenter, Randomized, Double-Blind, Placebo Control Study of IN-105 tablets [oral insulin] in Patients with Type 2 Diabetes Mellitus who have inadequate Glycemic Control on Optimal doses of Extended Release Metformin Tablets.
35. Biocon Limited, Bangalore Open label, randomized, Multicentric studies to Comapre safety and efficacy of Recombinant insulin aspart-biphasic and regular with NovoLog® Mix 70/30 and NovoRapid in T1DM and T2DM patients
36. Panacea Biotec Limited, New Delhi H1N1 pandemic influenza vaccine
37. V-Life Sciences Technology Pvt. Ltd., Pune Clinical Investigation of Galnobax for the treatment of Diabetic foot Ulcers
38.  

Biological E Limited., Hyderabad

A Multicentric, Parallel Randomised (2:1) Open Label Phase III Clinical Study To Evaluate The Immunogenicity And Safety Of BE’s Inactivated JE Vaccine In Healthy ≥1 To
39. Cadila Pharmaceuticals Ltd., Ahmedabad Clinical Development of Influenza Vaccines
Biogenerics/Biosimilars
40. Sun Pharmaceutical Industries Ltd., Gujarat Bevaciumab upto Pre-clinical studies
41. Gennova Biopharmaceuticals Limited, Pune Bio-similar interferon beta 1a: process development
42. Clonz Biotech Pvt. Ltd., Hyderabad Production of ranibizumab a recombinant humanized Anti-VEGF monoclonal antibody fragment (recombinant huFab V2) expressed in Hansenula Ploymorpha`
43. Navya Biologicals Pvt. Ltd. Development of novel intensified technology platform for production of low cost Mabs
44. Wockhardt Limited, Aurangabad Development of animal component free biosimilar recombinant protein therapeutics using mammalian platform technology
45. Serum Institute of India Limited, Pune Clinical Development of Polysialylated Erythropoietin
46. IMGENEX India Pvt. LTd., Bhubaneswar Development of High Expression plasmid vectors for production of biosimilar herceptin and other recombinant proteins and antibodies
47. Revelations Biotech Pvt. Ltd., Hyderabad Development of Novel and Economic process for production of recombinant human Insulin
48. Intas Biopharmaceuticals Pvt. Ltd., Ahemedabad Mucosal formulations of Parathyroid hormone (PTH)
49. Vivo Biotech Ltd., Andhra Pradesh Optimization of Scale-up/Purification and clinical grade material generation of recombinant Urate Oxidase
50. Inbiopro Solutions Pvt. Ltd., Bangalore Interferon Beta 1b process development
Stemcells
51. Stempeutics Research Pvt. Ltd., Bangalore A Randomized, Double Blind, multicentric, placebo controlled, Phase-II study assessing the safety and efficacy of Intraarterial (Hepatic) Ex-vivo cultured adult allogenic mesenchymal stem cells in patients with liver cirrhosis

 

52. Ravindranath GE Medical Associates Pvt. Ltd., Hyderabad Functional evaluation of autologous cell based therapy in cardiovascular diseases – Molecular imaging (An innovative non-invasiv technology”
Others
53. Perfint Healthcare Pvt. Ltd., Chennai Solution for planning, execution and confirmation of targeted ablation therapy
54. Strand Life Science, Bangalore Hepatotoxicity prediction platform
55. Frontier Lifeline Private Limited, Chennai Porcine Pulmonary Xenograft as a Conduit in Cardiovascular Surgery
56. (i)     Vinvish Technologies Pvt. Ltd., Trivendrum

(ii)   Centre for Earth Sciences, Trivandrum

(iii) Regional Cancer Centre, Thiruvananthapuram

 

Design and Development of photo dynamic therapy laser system

57. Agada Medical Technologies, Chennai Percutaneous Aortic Valve Technology
58. Merkel Haptic Systems Pvt. Ltd., Chennai Hi-fidelity affordable mannequin for effective CPR (Cardiopulmonary Resuscitation) Training
Agriculture
Transgenics
1. Maharashtra Hybrid Seeds Company Limited, Jalna Stress tolerant rice
2. Maharashtra Hybrid Seeds Company Limited Development of Sucking Insect Pest tolerant rice and cotton
3. Metahelix Life Sciences Private Limited, Bangalore A proposal for funding of deregulation trials of transgenic rice events expressing Metahelix synthetic Cry1C, Cry1Ac and Cry1Ab genes for tolerance to rice yellow stem borer, Scirpophaga incertulas
4. Metahelix Life Sciences Private Limited, Bangalore Deregul action trials phase I of transgenic maize events expressing Metahelix Synthetic Cry1C, Cry1Ac and Cry1Ab Genes for tolerance to stem and cob borers
5. (i)     Bioseed Research India Ltd., Hyderabad

(ii)   International Centre for Genetic Engineering and Biotechnology , New Delhi

 

 

Development of rice hybrids with improved drought and salinity stress tolerance

 

6. JK Agri Genetics Ltd., Hyderabad Development of Bt-rice with two cry genes
7. (i)     Mother Dairy Fruit and Vegetable Private Limited, Noida

(ii)   University of Delhi, South Campus, New Delhi

 

To conduct confined field trials and biosafety studies on genetically engineered Brassica juncea (Male sterility and restorer lines as pollination control mechanism) for heterosis breeding and yield improvement

Marker Assisted Selection
8. *Advanta India Limited, Secunderabad Multistacking genes to develop engineered rice with enhanced drought and multiple disease and pest resistance
9. Kaveri Seeds Company Ltd., Secunderabad Development of biotic stress resistant rice through conjunct use of bio-and hybrid technologies
10. (i)        Nirmal Seeds Pvt. Ltd., Jalgaon

(ii)      The Energy and Resources Institute, New Delhi

Development of nutritionally improved mustard (Brassica juncea) varieties/hybrids having low erucic acid and low glucosinolate content using marker assisted selection
11. Kaveri Seeds Company Ltd., Secunderabad Marker-assisted dissection of genetic basis of yield and improving yield potential under drought stress in Maize

 

12. (i)                 Krishidhan Seeds pvt. Ltd., Jalna

(ii)               ICRISAT, Andhra Pradesh

 

Genomics assisted accelerated product development of high yeilding pigeonpea hybrids

 

RNAi
13. (i)     **Advanta India Limited, Secunderabad

(ii)   Indian Agriculture Research Institute, New Delhi

RNAi and other cuting edge technological interventions to develop insect-pest diseases & viruses tolerant tomato hybrids for Indian & International markets
14. (i)     Sri Biotech Laboratories India Ltd., Hyderabad

(ii)   University of Delhi South Campus, Delhi

Control of Shoot and Fruit Borer Insect Pest (Leucinodes orbonalis Guenée) in Brinjal Through RNA interference
15. (i)     Ankur Seeds Pvt. Ltd., Nagpur

(ii)   International Centre for Genetic Engineering and Biotechnology , New Delhi

Third generation RNAi for engineering Tomato leaf curl (ToLCV) and tospovirus (GBNV) resistance in tomato
16. (i)     Nirmal Seeds Pvt. Ltd., Jalgaon

(ii)   University of Delhi, South Campus, New Delhi

 

Development of viral resistant okra using RNAi approached

Others
17. (i)        Bejo Sheetal Seeds Private Limited, Jalna

(ii)      International Centre for Genetic Engineering and Biotechnology , New Delhi

Development of ‘Herbicide & Stress tolerant’ transgenic Onion
18. (i)        Sri Biotech Laboratories India Ltd., Hyderabad

(ii)      International Crops Research Institute for the Semi-Arid Tropics, Hyderabad

 

Development of Actinomycetes based metabolites as delivery systems for soil health management in Groundnut

19. Chromous Biotech Pvt. Ltd., Bangalore Multiplexed fast-PCR based detection kit for major plant virus groups in India.
20. AP organics Pvt. Ltd., Punjab Project on value addition including potential neutraceuticals from derivatives of rice
21. (i)        Saveer Biotech, Greater Noida

(ii)      Indian Statistical Institute, Kolkata

Commercial Scale Production of Nanopesticides and Nanofungicides for Indian Agro-industry
22. Tata Chemicals Limited, Pune Inorganic and polymer nano-composites for micronutrient & pesticide delivery: Boosting crop health and yield.
23. Stellence PharmScience Ltd., Bangalore Development of a bio-efficacious value-added novel neem-based biopesticide formulation
Industrial
1. Rossari Biotech Ltd., Mumbai Viable Enzymes production using Agro waste/produce as raw material of Industrial/Feed and health care use with large viable Market/demand
2. Abhay Cotex India Pvt., Maharashtra Single step extraction of cottonseed with miscella refining
3. (i)        Anil Ltd., Ahmedabad

(ii)      National Chemical Laboratory (NCL), Pune

Development of Value added Corn steep liquor and powder suitable for food and fermentation industry upto pilot scale (1 TPD)
4. Myko Tech Pvt. Ltd., Mapusa

 

Enhanced production of extra-cellular melanin from various fungal sources for protection against UV and gamma radiations

 

Energy
1. Avesthagen Limited, Bangalore Development of Self-glucogenic Pearl Millet adapted for marginal lands
2. Richcore Lifesciences Pvt Ltd., Bangalore A process for Enhanced Ethanol Yield from Molasses Fermentation
3. Nagarjuna Fertilizers and Chemical Limited, Hyderabad Biological Hydrogen Production
4. (i)        Bharat Petroleum Corporation Limited, Greater Noida

(ii)      The Energy and Resources institute, New Delhi

Butanol production from lignocellulosic biomass
5. Thermax Limited, Pune Anaerobic Membrane Bioreactor (AnMBR) for Waste to Energy Solutions
6. India Glycols Limited, Kashipur Setting up a 10 ton Lignocellulosic biomass/day processing plant to produce about 3000 Litre ethanol/day
7. SPC Biotech, Hyderabad Bioconversion of Agricultural Waste from Mango kernel, to Polylactic acid a bio-plastic
8. Sea6 Energy, chennai Cost-effective offshore biomass production and bio-conversion to fuel – Bioenergy
9. Praj matrix, Pune Lignocellulosic Biomass to Ethanol Technology: Simultaneous Saccharification and Fermentation
Capacity Building through Infrastructure Support
1. Span Diagnostics Limited, Surat Establishment of cGMP compliant Bioprocess Facility for large-scale production of Microbial antigens and Monoclonal antibodies
2. Intas Biopharmaceuticals Private Limited, Ahmedabad Facility for high end structural and functional characterization of protein therapeutics and peptides
3. Gennova Biopharmaceuticals Limited, Pune State of art cGMP prodution facility metting regulatory requirement for production of recombinant bio-therapeutics
4. Celestial Biologicals Ltd., Ahmedabad Scale-up of Plasma Fractionatin Facility for High Value Product
Bio-informatics
1. (i) Persistent Systems, Maharashtra

(ii) Indian Institute of Technology (IIT), Mumbai

(iii) Indian Institute of Science Education and Research (IISER), Pune

(iv)             National Bureau of Animal Genetic Resources (NBAGR), Haryana

 

 

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